Encorium Group, Inc. Announces $3.8 Million Contract For Phase 2 Clinical Trial in Herpes Zoster (Shingles)
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Encorium Group, Inc. (Nasdaq: ENCO), a leader in the design,
development, and management of complex clinical trials and patient
registries for many of the world's leading pharmaceutical and
biotechnology companies, today announced the signing of a $3.8 million
contract for a Phase 2 clinical trial of a new antiviral agent to treat
herpes zoster (shingles). Encorium will provide multiple services
including program consulting, project management, site management and
monitoring, data management, biostatistical support, and medical
writing. Revenue recognition will begin during the current second
quarter and continue on a proportional performance basis over the life
of the contract as services are performed.
Kenneth M. Borow, M.D., Encorium Group’s
President and Chief Executive Officer, commented, "We
are delighted to have been chosen by this new client to work on its
Phase 2b trial involving a new antiviral agent for the treatment of
herpes zoster (shingles). The program combines our expertise gained from
operationally overseeing the highly successful 38,546 subject Shingles
Prevention Trial with the patient recruitment experience obtained
recently from clinical trials relating to antiviral treatments for acute
influenza. Thus, this new contract represents an excellent blend of our
infectious disease therapeutic area expertise and our highly relevant
on-the-ground clinical operations capabilities and experience. We look
forward to a long and mutually beneficial collaborative relationship
with the sponsoring company.”
Dr. Borow concluded, "We are now beginning to
see the benefits of our expanded global business development efforts.
This $3.8 million contract is a concrete example of the value that the
biopharmaceutical industry places on our integrated offering of
consulting services, operational expertise, proactive planning, and
medical education capabilities. We anticipate announcing additional
signed contracts over the next several months as well as further
elaborating on other initiatives that we are pursuing.” About Herpes Zoster (Shingles)
Herpes zoster is caused by reactivation of the varicella zoster virus
(VZV), the same virus that causes chickenpox. This can occur years or
even decades after exposure to naturally occurring or vaccine type VZV.
A decline in specific cell mediated immune response to VZV as observed
in the elderly population and immunosuppressed hosts is regarded as the
major precipitant for inducing VZV reactivation. It is estimated that
500,000 to 1 million cases of zoster are diagnosed annually in the U.S.
Both genders are equally affected. About 20% of people who have had
chicken pox will get zoster at some point during their lifetime. Zoster
is characterized as a localized disease that usually involves only one
side of the body. The rash that occurs with Zoster is often associated
with significant pain. The pain symptoms may last many months after the
rash has resolved. Use of antiviral therapy at the time of initial
diagnosis is associated with a reduction in pain duration. The overall
goals of antiviral therapy are to promote more rapid healing of skin
lesions and to lessen the severity and duration of pain associated with
the disease.
About Encorium Group, Inc.
Encorium Group, Inc. is a global clinical research organization that is
a leader in the design and management of complex clinical trials and
Patient Registries for the pharmaceutical, biotechnology and medical
device industries. The Company’s mission is to
provide its clients with high quality, full-service support for their
biopharmaceutical and medical device development programs. Encorium
offers therapeutic expertise, experienced team management and advanced
technologies. The Company has drug and biologics development as well as
clinical trial experience across a wide variety of therapeutic areas
such as infectious diseases, cardiovascular, vaccines, oncology,
endocrinology/metabolism, diabetes, gene therapy, immunology, neurology,
gastroenterology, dermatology, hepatology, women’s
health and respiratory medicine. Encorium believes that its leadership
in the design of complex clinical trials, its therapeutic expertise and
commitment to excellence, and its application of innovative
technologies, offer its clients a means to more quickly and cost
effectively move products through the clinical development process.
Encorium is headquartered in Wayne, Pennsylvania with its European base
of operations in Espoo, Finland. The Company has a geographic footprint
that includes over one billion people in North America,
Western/Central/Eastern Europe, Scandinavia, and the Baltics.
This press release contains forward-looking statements identified by
words such as "estimate,” "project,” "expect,” "intend,” "believe,” "anticipate” and
similar expressions. Actual results might differ materially from those
projected in, expressed in or implied by the forward-looking statements.
Potential risks and uncertainties that could affect the Company's future
operating results and financial condition include, without limitation:
(i) our success in attracting new business and retaining existing
clients and projects; (ii) the size, duration, and timing of clinical
trials we are currently managing may change unexpectedly; (iii) the
termination, delay or cancellation of clinical trials we are currently
managing could cause revenues to decline unexpectedly; (iv) the timing
difference between our receipt of contract milestone or scheduled
payments and our incurring costs to manage these trials; (v) outsourcing
trends in the pharmaceutical, biotechnology and medical device
industries; (vi) the ability to maintain profit margins in a competitive
marketplace; (vii) our ability to attract and retain qualified
personnel; (viii) the sensitivity of our business to general economic
conditions; (ix) other economic, competitive, governmental and
technological factors affecting our operations, markets, products,
services and prices; (x) announced awards received from existing and
potential customers are not definitive until fully negotiated contracts
are executed by the parties; (xi) our backlog may not be indicative of
future revenues and may not generate the revenues expected; (xii) our
ability to successfully integrate the businesses of Encorium and
Remedium Oy which we acquired on November 1, 2006; and (xiii) ability of
the combined businesses to operate successfully, generate revenue growth
and operating profits. You should not place any undue reliance on these
forward looking statements which speak only as of the date of this press
release. Additional information concerning factors that might affect our
business or stock price which could cause actual results to materially
differ from those in forward-looking statements is contained in Encorium
Group's SEC filings, including its Annual Report on Form 10-K for the
year ended December 31, 2006 and other periodic reports under the
Securities Exchange Act of 1934, as amended, copies of which are
available upon request from Encorium Group's investor relations
department or The Equity Group Inc.