Plexera Inks Exclusive Content Deal for DNA-based Protein Chips
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Plexera Bioscience LLC, a wholly owned subsidiary of Lumera Corporation
(NASDAQ:LMRA), announced today an option agreement with Auguron
Biosciences, Inc, giving them rights to exclusive access to use Auguron’s
Nucleic Acid Programmable Protein Array (NAPPA) technology on the
Plexera Kx™ Array Platform.
NAPPA technology was developed at the Harvard Institute of Proteomics
and is protected by several issued and pending patents, licensed
exclusively to Auguron Biosciences. The technology enables fresh,
functional proteins to be generated on high density microchips from
surface printed DNA.
"Plexera’s business
model is focused on developing high value content consumables,”
said Dr. Joe Vallner, Plexera Chairman and Chief Executive Officer. "We
believe Auguron’s NAPPA technology will allow
us to offer a unique and compelling assortment of high quality and
unique content to both the life science and pharmaceutical markets
giving us a significant competitive advantage and becoming a cornerstone
of our content development.”
Auguron was formed in early 2007 to commercialize developments at the
Harvard Institute for Proteomics (HIP). "Empowering
Plexera’s label-free Kx™
Array platform with NAPPA will provide access to a virtually unlimited
source of protein content with very high levels of control over both
composition and functionality,” said Jim
Richey, Co-Founder and Chief Executive of Auguron. "By
printing DNA and expressing proteins in-situ, NAPPA skips the expense,
time, yield and activity consuming steps associated with conventional
printed protein arrays. Combining Plexera’s
ability to interrogate interactions of every array element
simultaneously, without the use of labels, presents previously
unimagined investigative opportunities for complex biological systems.”
While conventional label-free platforms look at one or several spots at
a time, Plexera’s platform is designed to
monitor thousands of elements simultaneously. "It
is this capability combined with NAPPA’s
power to access every gene in the genome that makes this combination so
compelling,” Richey continued.
The Agreement provides Plexera exclusive access for a one year period
with terms for a one year extension. Plexera will test and develop NAPPA
as a content source for Kx™ in collaboration
together with Auguron and other strategic partners. At any time during
the period, Plexera may exercise the option to negotiate an exclusive
license to NAPPA within the field of detection by or depending upon SPR,
the label free detection method used in the Kx™
Array platform. Although the financial details were not disclosed, the
companies have stated that the fundamental terms of the license are
pre-agreed in the option. Should Plexera exercise the option, the
companies envision a strategic relationship where Auguron produces and
supplies NAPPA enabled microchips to Plexera.
"2007 was a very exciting year for Plexera as
we reached several important milestones critical to building a
foundation for long term success,” continued
said Vallner. "The internal development teams
alongside our external partners are focused and on track to launch the
Kx5™ biosensor instrument in May, 2008 to the
therapeutic antibody development market. This option agreement announced
today provides us with the protection we need to fully investigate and
develop NAPPA and Kx™ into an integrated
solution that will broaden our product offering to provide unique
solutions to drug and vaccine discovery and development and basic
research,” About Auguron Biosciences, Inc.
Auguron is a development stage, de novo start up founded by Dr. Joshua
LaBaer, head of the Harvard Institute of Proteomics, his principle
investigator, Dr. Niro Ramachandran and Mr. James Richey, an industry
seasoned executive and CEO of Auguron. Auguron holds the exclusive
license to the NAPPA array technology developed at Harvard and is
forming an operation to produce NAPPA-based array products.
About Plexera Biosciences LLC
Plexera Biosciences LLC., a wholly owned subsidiary of Lumera
Corporation (NASDAQ:LMRA), develops and manufactures advanced analytical
tools and methods that enable life science researchers to probe the
human proteome for improved diagnostics, therapeutics, and knowledge of
the human condition. For more information, please visit www.plexera.com.
Certain statements contained in this release are forward-looking
statements that involve a number of risks and uncertainties. Factors
that could cause actual results to differ materially from those
projected in the company's forward-looking statements include the
following: market acceptance of our technologies and products; our
ability to obtain financing; our financial and technical resources
relative to those of our competitors; our ability to keep up with rapid
technological change; government regulation of our technologies; our
ability to enforce our intellectual property rights and protect our
proprietary technologies; the ability to obtain additional contract
awards and to develop partnership opportunities; the timing of
commercial product launches; the ability to achieve key technical
milestones in key products; and other risk factors identified from time
to time in the company's SEC reports, including its Annual Report on
Form 10-K, and its Quarterly Reports on Form 10-Q.