Prospect Medical Holdings to Conduct Fourth Quarter and Year-End Conference Call on January 8, 2009

Prospect Medical Holdings, Inc. (NYSE Alternext US: PZZ) ("Prospect”), which owns and operates four community-based hospitals and manages the medical care of approximately 194,000 HMO enrollees in southern California, will host a conference call to discuss its previously announced results for the fourth quarter and fiscal year ended September 30, 2008 (see press release dated December 29, 2008), current operating initiatives, progress on addressing legacy business issues, and initiatives for 2009.

The conference call will also be broadcast live over the Internet at the following link:

http://investor.shareholder.com/media/eventdetail.cfm?eventid=63447&CompanyID=PROSPECT&e=1&mediaKey=FD1088B6F9BDB79FFAEA6E426404E661.

If you are unable to participate in the live call, the conference call will be archived and can be accessed for approximately 30 days.

ABOUT PROSPECT MEDICAL HOLDINGS

Prospect Medical Holdings operates four community-based hospitals in the greater Los Angeles area and manages the medical care of individuals enrolled in HMO plans in Southern California, through a network of approximately 14,000 specialist and primary care physicians.

This press release contains forward-looking statements. Additional written or oral forward-looking statements may be made by Prospect from time to time, in filings with the Securities and Exchange Commission, or otherwise. Statements contained herein that are not historical facts are forward-looking statements. Investors are cautioned that forward-looking statements, including the statements regarding anticipated or expected results, involve risks and uncertainties which may affect the Company's business and prospects, including those outlined in Prospect's Form 10-K filed on December 29, 2008, as well as risks and uncertainties arising from Prospect's acquisition of Alta and ProMed, and the debt incurred by Prospect in connection with those acquisitions. Any forward-looking statements contained in this press release represent our estimates only as of the date hereof, or as of such earlier dates as are indicated, and should not be relied upon as representing our estimates as of any subsequent date. While we may elect to update forward-looking statements at some point in the future, we specifically disclaim any obligation to do so, even if our estimates change.