Press Release: Basilea provides corporate update -2-


Werte in diesem Artikel
Aktien

60.00 EUR 3.00 EUR 5.26 %

5. T. Helsten, S. Elkin, E. Arthur et al. The FGFR landscape in cancer:

Analysis of 4,853 tumors by next-generation sequencing. Clinical Cancer

Werbung

Research 2016 (22), 259-267

6. P. McSheehy, F. Bachmann, N. Forster-Gross et al. Derazantinib (DZB): A

dual FGFR/CSF1R-inhibitor active in PDX-models of urothelial cancer.

Molecular Cancer Therapeutics 2019 (18), 12 supplement, pp. LB-C12

7. M. A. Cannarile, M. Weisser, W. Jacob et al. Colony-stimulating factor 1

receptor (CSF1R) inhibitors in cancer therapy. Journal for ImmunoTherapy

Werbung

of Cancer 2017, 5:53

8. Y. Zhu, B. L. Knolhoff, M. A. Meyer et al. CSF1/CSF1R Blockade reprograms

tumor-infiltrating macrophages and improves response to T cell checkpoint

immunotherapy in pancreatic cancer models. Cancer Research 2014 (74),

5057-5069

9. E. Peranzoni, J. Lemoine, L. Vimeux et al. Macrophages impede CD8 T cells

from reaching tumor cells and limit the efficacy of anti--PD-1 treatment.

Werbung

Proceedings of the National Academy of Science of the United States of

America 2018 (115), E4041-E4050

10. V. Mazzaferro, B. F. El-Rayes, M. Droz dit Busset et al. Derazantinib

(ARQ 087) in advanced or inoperable FGFR2 gene fusion-positive

intrahepatic cholangiocarcinoma. British Journal of Cancer 2019 (120),

165-171. ClinicalTrials.gov identifier: NCT01752920

11. ClinicalTrials.gov identifier: NCT03230318

12. ClinicalTrials.gov identifier: NCT04045613. Tecentriq(R) is a registered

trademark of Hoffmann-La Roche Ltd.

13. J. Pohlmann, F. Bachmann, A. Schmitt-Hoffmann et al. BAL101553: An

optimized prodrug of the microtubule destabilizer BAL27862 with superior

antitumor activity. American Association for Cancer Research (AACR)

annual meeting 2011, abstract 1347; Cancer Research 2011, 71 (8

supplement)

14. ClinicalTrials.gov identifier: NCT02490800

15. ClinicalTrials.gov identifier: NCT03250299

16. ClinicalTrials.gov identifier: NCT02895360

17. A. Sharmq, A. Broggini-Tenzer, V. Vuong et al. The novel microtubule

targeting agent BAL101553 in combination with radiotherapy in

treatment-refractory tumor models. Radiotherapy Oncology 2017 (124),

433-438

18. G. E. Duran, H. Lane, F. Bachmann et al. In vitro activity of the novel

tubulin active agent BAL27862 in MDR1(+) and MDR1(-) human breast and

ovarian cancer variants selected for resistance to taxanes. American

Association for Cancer Research (AACR) annual meeting 2010, abstract

4412; Cancer Research 2010, 70 (8 supplement)

19. F. Bachmann, K. Burger, G. E. Duran et al. BAL101553 (prodrug of

BAL27862): A unique microtubule destabilizer active against drug

refractory breast cancers alone and in combination with trastuzumab.

American Association for Cancer Research (AACR) annual meeting 2014,

abstract 831; Cancer Research 2014, 74 (19 supplement)

20. A. Schmitt-Hoffmann, D. Klauer, K. Gebhardt et al. BAL27862: a unique

microtubule-targeted agent with a potential for the treatment of human

brain tumors. AACR-NCI-EORTC conference 2009, abstract C233; Molecular

Cancer Therapeutics 2009, 8 (12 supplement)

21. A. C. Mladek, J. L. Pokorny, H. Lane et al. The novel tubulin-binding

'tumor checkpoint controller' BAL101553 has anti-cancer activity alone

and in combination treatments across a panel of GBM patient-derived

xenografts. American Association for Cancer Research (AACR) annual

meeting 2016, abstract 4781; Cancer Research 2016, 76 (14 supplement)

22. R. Bergès, A. Tchoghandjian, S. Honoré et al. The novel

tubulin-binding checkpoint activator BAL101553 inhibits EB1-dependent

migration and invasion and promotes differentiation of glioblastoma

stem-like cells. Molecular Cancer Therapeutics 2016 (15), 2740-2749

23. A. E. Prota, F. Danel, F. Bachmann et al. The novel

microtubule-destabilizing drug BAL27862 binds to the colchicine site of

tubulin with distinct effects on microtubule organization. Journal of

Molecular Biology 2014 (426), 1848-1860

24. F. Bachmann, K. Burger, H. Lane. BAL101553 (prodrug of BAL27862): the

spindle assembly checkpoint is required for anticancer activity. American

Association for Cancer Research (AACR) annual meeting 2015, abstract

3789; Cancer Research 2015, 75 (15 supplement)

Attachments

-- Press release (PDF).pdf

https://ml-eu.globenewswire.com/Resource/Download/e4f177c7-3cc6-4506-b912-69eb84d2bc9a

(END) Dow Jones Newswires

May 28, 2020 01:15 ET (05:15 GMT)

Aktuelle Basilea Pharmaceutica Aktie News

Werbung

Basilea Pharmaceutica Analysen

Um die Übersicht zu verbessern, haben Sie die Möglichkeit, die Analysen für Basilea Pharmaceutica nach folgenden Kriterien zu filtern.

Alle: Alle Empfehlungen

Buy: Kaufempfehlungen wie z.B. "kaufen" oder "buy"
Hold: Halten-Empfehlungen wie z.B. "halten" oder "neutral"
Sell: Verkaufsempfehlungn wie z.B. "verkaufen" oder "reduce"
DatumRatingAnalyst
08.02.13 Basilea Pharmaceutica halten Vontobel Research
07.02.13 Basilea Pharmaceutica halten Vontobel Research
10.12.12 Basilea Pharmaceutica hold Vontobel Research
10.12.12 Basilea Pharmaceutica buy Sarasin Research
22.11.12 Basilea Pharmaceutica hold Vontobel Research