Press Release: Basilea provides corporate update -2-
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5. T. Helsten, S. Elkin, E. Arthur et al. The FGFR landscape in cancer:
Analysis of 4,853 tumors by next-generation sequencing. Clinical Cancer
Research 2016 (22), 259-267
6. P. McSheehy, F. Bachmann, N. Forster-Gross et al. Derazantinib (DZB): A
dual FGFR/CSF1R-inhibitor active in PDX-models of urothelial cancer.
Molecular Cancer Therapeutics 2019 (18), 12 supplement, pp. LB-C12
7. M. A. Cannarile, M. Weisser, W. Jacob et al. Colony-stimulating factor 1
receptor (CSF1R) inhibitors in cancer therapy. Journal for ImmunoTherapy
of Cancer 2017, 5:53
8. Y. Zhu, B. L. Knolhoff, M. A. Meyer et al. CSF1/CSF1R Blockade reprograms
tumor-infiltrating macrophages and improves response to T cell checkpoint
immunotherapy in pancreatic cancer models. Cancer Research 2014 (74),
5057-5069
9. E. Peranzoni, J. Lemoine, L. Vimeux et al. Macrophages impede CD8 T cells
from reaching tumor cells and limit the efficacy of anti--PD-1 treatment.
Proceedings of the National Academy of Science of the United States of
America 2018 (115), E4041-E4050
10. V. Mazzaferro, B. F. El-Rayes, M. Droz dit Busset et al. Derazantinib
(ARQ 087) in advanced or inoperable FGFR2 gene fusion-positive
intrahepatic cholangiocarcinoma. British Journal of Cancer 2019 (120),
165-171. ClinicalTrials.gov identifier: NCT01752920
11. ClinicalTrials.gov identifier: NCT03230318
12. ClinicalTrials.gov identifier: NCT04045613. Tecentriq(R) is a registered
trademark of Hoffmann-La Roche Ltd.
13. J. Pohlmann, F. Bachmann, A. Schmitt-Hoffmann et al. BAL101553: An
optimized prodrug of the microtubule destabilizer BAL27862 with superior
antitumor activity. American Association for Cancer Research (AACR)
annual meeting 2011, abstract 1347; Cancer Research 2011, 71 (8
supplement)
14. ClinicalTrials.gov identifier: NCT02490800
15. ClinicalTrials.gov identifier: NCT03250299
16. ClinicalTrials.gov identifier: NCT02895360
17. A. Sharmq, A. Broggini-Tenzer, V. Vuong et al. The novel microtubule
targeting agent BAL101553 in combination with radiotherapy in
treatment-refractory tumor models. Radiotherapy Oncology 2017 (124),
433-438
18. G. E. Duran, H. Lane, F. Bachmann et al. In vitro activity of the novel
tubulin active agent BAL27862 in MDR1(+) and MDR1(-) human breast and
ovarian cancer variants selected for resistance to taxanes. American
Association for Cancer Research (AACR) annual meeting 2010, abstract
4412; Cancer Research 2010, 70 (8 supplement)
19. F. Bachmann, K. Burger, G. E. Duran et al. BAL101553 (prodrug of
BAL27862): A unique microtubule destabilizer active against drug
refractory breast cancers alone and in combination with trastuzumab.
American Association for Cancer Research (AACR) annual meeting 2014,
abstract 831; Cancer Research 2014, 74 (19 supplement)
20. A. Schmitt-Hoffmann, D. Klauer, K. Gebhardt et al. BAL27862: a unique
microtubule-targeted agent with a potential for the treatment of human
brain tumors. AACR-NCI-EORTC conference 2009, abstract C233; Molecular
Cancer Therapeutics 2009, 8 (12 supplement)
21. A. C. Mladek, J. L. Pokorny, H. Lane et al. The novel tubulin-binding
'tumor checkpoint controller' BAL101553 has anti-cancer activity alone
and in combination treatments across a panel of GBM patient-derived
xenografts. American Association for Cancer Research (AACR) annual
meeting 2016, abstract 4781; Cancer Research 2016, 76 (14 supplement)
22. R. Bergès, A. Tchoghandjian, S. Honoré et al. The novel
tubulin-binding checkpoint activator BAL101553 inhibits EB1-dependent
migration and invasion and promotes differentiation of glioblastoma
stem-like cells. Molecular Cancer Therapeutics 2016 (15), 2740-2749
23. A. E. Prota, F. Danel, F. Bachmann et al. The novel
microtubule-destabilizing drug BAL27862 binds to the colchicine site of
tubulin with distinct effects on microtubule organization. Journal of
Molecular Biology 2014 (426), 1848-1860
24. F. Bachmann, K. Burger, H. Lane. BAL101553 (prodrug of BAL27862): the
spindle assembly checkpoint is required for anticancer activity. American
Association for Cancer Research (AACR) annual meeting 2015, abstract
3789; Cancer Research 2015, 75 (15 supplement)
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May 28, 2020 01:15 ET (05:15 GMT)
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