Three Leading Health Systems Join the Aegis Digital Consortium to Build and Deploy Healthtech Solutions

NEW YORK, Sept. 15, 2025 /PRNewswire/ -- Aegis Ventures announced three health systems– Yale New Haven Health System, Keck Medicine of USC, and Hartford HealthCare–have joined the Aegis Digital Consortium, a collaboration of fourteen leading regional health systems across the U.S. to develop AI-powered healthtech solutions that address healthcare's most pressing challenges. These health systems will innovate together with Aegis to co-develop, invest in, and deploy new technologies to enable them to better care for the communities they serve, while generating diversified sources of revenue.

"Joining the Aegis Digital Consortium builds upon the mission of Yale New Haven Health's Center for Health Care Innovation, by expanding our efforts for creating, identifying, fostering and scaling healthcare innovations," said Pamela Sutton-Wallace, President, Yale New Haven Health. "Together with other leading health systems, we can enhance the lives of people we serve through disruptive innovations and initiatives that transform healthcare delivery."

"One of our top priorities at Keck Medicine of USC is to accelerate health sciences innovation by combining AI-driven technologies with transformative, compassionate patient care," said Aman Mahajan, MD, PhD, who leads Health Sciences Innovation and Transformation for USC Health. "We've been impressed by the progress made by the Aegis Digital Consortium since its launch, and we're delighted to join this community of practice to co-develop new solutions alongside Aegis and other leading health systems."

"At Hartford HealthCare, we are committed to becoming the most consumer-centric healthcare system.  Over the past ten years, we have built a dynamic innovation ecosystem platform that brings together a diverse network of stakeholders — from world-class startups and entrepreneurs to leading global academic institutions, venture capital firms, and corporate partners," said Barry Stein, MD, MBA, Chief Clinical Innovation Officer and Chief Medical Informatics Officer, Hartford HealthCare. "We look forward to Aegis collaborating meaningfully to this ecosystem, helping us accelerate innovation and advance our mission to transform healthcare."

Aegis Digital Consortium members include many of the nation's most respected health systems, such as Endeavor Health, Indiana University Health, Memorial Hermann Health System, Northwell Health, Novant Health, Ochsner Health, The Ohio State University Wexner Medical Center, Sharp HealthCare, Stanford Health Care, UPMC, Vanderbilt Health. Together, they represent nearly 8% of U.S. healthcare, half a million employees, and over $100B in operating revenue.

"These three renowned health systems reflect a demonstrated commitment to transformation and innovation leadership at the local, regional, national, and international level," said Dr. John Noseworthy, Chairman of the Aegis Digital Consortium and Emeritus CEO of Mayo Clinic. "We are thrilled to have their thought leadership and partnership to strengthen our national consortium of 14 members as we collaborate to create and scale the next wave of healthtech companies to tackle some of healthcare's toughest challenges."

About Aegis Ventures
Aegis Ventures is a NYC-based venture studio that partners with entrepreneurs and health systems to launch and scale meaningful healthtech startups that drive healthcare forward. The Aegis platform combines deep insights, aligned capital, and proprietary access to customers to substantially increase the velocity and success rate of the new companies we build. To learn more about Aegis, visit our website and follow us on LinkedIn.

About Yale New Haven Health
Yale New Haven Health (YNHHS), the largest and most comprehensive healthcare system in Connecticut, is recognized for advanced clinical care, quality, service, cost effectiveness and commitment to improving the health status of the communities it serves. YNHHS includes five hospitals – Bridgeport, Greenwich, Lawrence + Memorial, Westerly and Yale New Haven hospitals, several specialty networks and Northeast Medical Group, a non-profit physician foundation with several hundred community-based and hospital-employed physicians. YNHHS is affiliated with Yale University and YSM's clinical physician practice, Yale Medicine, which is the largest academic multi-specialty practice in New England. YNHHS and Yale partner on clinical care, education and research, bringing the latest discoveries, technology and therapies to patients. www.ynhhs.org

About Keck Medicine of USC
Keck Medicine of USC is the University of Southern California's medical enterprise, one of only two university-based medical systems in the Los Angeles area. Keck Medicine combines academic excellence, world-class research and state-of-the-art facilities to provide highly specialized care for some of the most acute patients in the country.
Its internationally renowned physicians and scientists provide world-class patient care at Keck Hospital of USC, USC Norris Cancer Hospital, USC Verdugo Hills Hospital, USC Arcadia Hospital and more than 100 unique clinics in Los Angeles, Orange, Kern, Tulare and Ventura counties as well as Las Vegas.
Keck Medical Center of USC, which includes Keck Hospital and USC Norris Cancer Hospital, is among the top 50 hospitals in the country in seven specialties, as well as among the top ten hospitals in California and top five hospitals in metro Los Angeles, according to the U.S. News & World Report 2025-26 Best Hospitals rankings.
For more information, visit KeckMedicine.org

About Hartford HealthCare
With 43,000 dedicated colleagues and a bold vision for the future, Hartford HealthCare is transforming healthcare across Connecticut and beyond—enhancing access, affordability, health equity, and excellence. Spanning more than 500 locations across 185 towns and cities, our comprehensive care-delivery system is built to serve every community, every day.
From world-class hospitals—including two tertiary-level teaching hospitals, an acute-care community teaching hospital, an acute-care hospital and trauma center, and three community hospitals—to an expansive network of behavioral health services, multispecialty physician groups, urgent and virtual care, surgery centers, home care, senior care, rehabilitation, and mobile neighborhood health programs, Hartford HealthCare is there when and where it matters most.
Hartford HealthCare touches the lives of 27,000 people every single day, delivering unparalleled care through its unique Institute Model—bringing together leading experts in neuroscience, cancer, digestive health, heart and vascular care, orthopedics, and urology & kidney health to provide a unified, high standard of care at the most affordable cost.
Recognized nationally for patient safety and clinical excellence, Hartford HealthCare was the only health system in country awarded the prestigious "Quest for Quality Prize" from the American Hospital Association and boasts Leapfrog A-ratings across all its hospitals—making Hartford HealthCare one of the safest healthcare systems in the country.
Join us on our journey to redefine healthcare. Visit www.HartfordHealthCare.org and stay connected through our newsletters and social media.

Media Contact:
Kara Spak for Aegis Ventures
kara@12080group.com 

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SOURCE Aegis Venture Partners LLC