Corteva Announces Groundbreaking, Nature-Inspired Solutions to Control Insects, Help Farmers Effectively Protect Yield

Company's First Bioinsecticide Helps Protect Apples, Oranges, Wheat, Rice, Corn, Among Other Crops

INDIANAPOLIS, Nov. 5, 2025 /PRNewswire/ -- Globally, thousands of species of insects threaten crop yield by feeding on plants, transmitting diseases and damaging plant tissues, which leads to significant losses: an estimated 20%-40% for crops globally¹ like wheat, corn and rice, at an estimated cost of $70 billion².

Today, Corteva announced two new crop protection solutions, one of natural origin and the other naturally inspired, to combat these destructive pests. ⁴

• Goltrevo™bioinsecticide is a broad-spectrum, microbial-based solution designed to combat some sap-feeding and chewing insects, including whiteflies, aphids and the devasting corn leafhopper, which spreads the bacterial pathogen responsible for corn stunt disease and can cause yield losses of up to 70%³. Goltrevo is the first bioinsecticide in Corteva's Biologicals portfolio. 
  
  
• Varpelgo™ active is a next-generation insecticide developed by closely studying the structure and function of the naturally occurring Qalcova™ active, using nature as an inspiration to design a novel solution to control chewing pests in fruits and vegetables, row crops and rice.

"Innovation is at the core of our crop protection business and today's announcement further advances our global leadership," said Robert King, executive vice president, crop protection for Corteva. "These new insect management solutions complement our existing portfolio of leading biological and insecticide products and will help farmers better manage costly insect damage while supporting our vision of providing more sustainable solutions, improving farmer productivity and strengthening global food security."

Goltrevo is a best-in-class formulation based on a novel strain of the entomopathogenic fungus Beauveria bassiana 203, originally isolated from palm weevil beetles. This novel bioinsecticide will target some sap-feeding insects, such as corn leafhoppers, whiteflies, aphids and stinkbugs, as well as chewing insects, including several species of root-feeding worms, beetles, and destructive caterpillars.

With Goltrevo, growers can expect a longer shelf life and lower potential for the development of resistance, ensuring stability and usability across different farming practices and crops, including corn, soybean, sugarcane, pastures, fruits and vegetables. Commercial sales are expected to begin as early as 2027 in Latin America, pending applicable regulatory approvals. ⁴

Varpelgo active provides highly effective control of chewing insects, including diamondback moths, armyworms, loopers, and several species of borers, beetles, weevils and thrips, in key crops such as soybeans, corn, rice, tree nuts, sugarcane, fruits and vegetables, across all global regions. It also offers a new seed applied technology solution to protect the seed and seedling from wireworm.

With a favorable ecological profile and low use rates, Varpelgo will fit within farmers' integrated pest management and insect resistance management programs, giving them a new rotational choice for chewing insect control. The first commercial sales are expected in Asia Pacific and Latin America in the early 2030s, pending completion of field trials and applicable regulatory reviews. ⁴

^1,2Researchers Helping Protect Crops From Pests | NIFA

³Corn Stunt Disease

⁴ Goltrevo™ and Varpelgo™ active are not registered for sale in any jurisdiction, and references to expected date of registration are estimates and subject to change.  The information here is not an offer for sale.

About Corteva

Corteva, Inc. (NYSE: CTVA) is a global pure-play agriculture company that combines industry-leading innovation, high-touch customer engagement and operational execution to profitably deliver solutions for the world's most pressing agriculture challenges. Corteva generates advantaged market preference through its unique distribution strategy, together with its balanced and globally diverse mix of seed, crop protection, and digital products and services. With some of the most recognized brands in agriculture and a technology pipeline well positioned to drive growth, the company is committed to maximizing productivity for farmers, while working with stakeholders throughout the food system as it fulfills its promise to enrich the lives of those who produce and those who consume, ensuring progress for generations to come. More information can be found at www.corteva.com.

Cautionary Statement on Forward-Looking Statements

This press release contains certain estimates and forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended, which are intended to be covered by the safe harbor provisions for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995, and may be identified by their use of words like "expects," "will," "intends," "believes," "estimates," or "can" other words of similar meaning. All statements that address expectations or projections about the future, including statements about Corteva's expectations related to regulatory approvals, product development and commercialization, product offerings and product, financial or sustainability performance are forward-looking statements. Corteva disclaims and does not undertake any obligation to update or revise any forward-looking statement, except as required by applicable law. A detailed discussion of some of the significant risks and uncertainties which may cause results and events to differ materially from such forward-looking statements or other estimates is included in the "Risk Factors" section of Corteva's Annual Report on Form 10-K, and as modified by subsequent reports on Form 10-Q and Current Reports on Form 8-K.

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SOURCE Corteva Agriscience