Improving Clinical Response Signaling in Rare Disease Studies with Targeted Endpoint Data Quality Programs, Upcoming Webinar Hosted by Xtalks

In this free webinar, gain insight into strategies to improve data quality monitoring in rare disease clinical trials, including eCOA form optimization, enhanced rater training and the use of combined algorithmic, data-based review and risk-based expert data review. Attendees will learn about the use of central rating with highly trained clinicians. The featured speaker will share methods for determining meaningful within-patient change thresholds.

TORONTO, Sept. 9, 2025 /PRNewswire/ -- Rare disease clinical trials face unique challenges due to small patient populations, heterogeneous disease presentations and complex neurocognitive assessments. These factors exacerbate the difficulty of detecting meaningful treatment effects, making it crucial for study teams to adopt innovative strategies to enhance signal detection and improve decision-making both during and after rare disease studies.

In this webinar, the speaker, a rare disease expert, will share proven tactics and clinical trial case examples of how rare disease study teams are improving clinical response signaling using targeted approaches to endpoint data quality.

In particular, the speaker will share details regarding:

     -     eCOA form optimization to address common rater errors before they occur

     -     Optimizing rater qualification and training programs for rare disease trials

     -     Data quality monitoring using both algorithmic, data-based review as well as risk-based expert review

     -     Central rating using small groups of highly trained clinicians to administer/score scales remotely

     -     Methods for determining meaningful within-patient change thresholds

Register for this webinar to gain insights into how teams are overcoming the unique challenges of rare disease studies and improving clinical response signaling.

Join Pamela Ventola, PhD, Chief Science Officer, Cogstate, for the live webinar on Tuesday, September 30, 2025, at 11am EDT (4pm BST/UK).

For more information or to register for this event, visit Improving Clinical Response Signaling in Rare Disease Studies with Targeted Endpoint Data Quality Programs.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars and digital content to the global life science, food, healthcare and medical device communities. Every year, thousands of industry practitioners (from pharmaceutical, biotechnology, food, healthcare and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps professionals stay current with industry developments, regulations and jobs. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks, visit www.xtalks.com

For information about hosting a webinar, visit www.xtalks.com/why-host-a-webinar/

Contact:
Vera Kovacevic
Tel: +1 (416) 977-6555 x371
Email: vkovacevic@xtalks.com

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